Silence Therapeutics Notice of Annual General Meeting and Publication of Annual Report

Silence Therapeutics plc (LON:SLN), a leader in the discovery, delivery, and development of novel RNA therapeutics for the treatment of serious diseases with unmet medical need, announced today that its annual report and financial statements for the year ended 31 December 2017 (“Annual Report and Accounts”) is available for download on the Company’s website www.silence-therapeutics.com. The Annual Report and Accounts will be posted to shareholders on 16 March 2018.

This year’s Annual General Meeting (“AGM”) of the Company will be held on 23 April 2018 at 10am. The Notice of the AGM will be posted to shareholders on or before 16 March 2018, when it will also be made available on the Company’s website. The AGM will be held at the offices of Silence Therapeutics Plc, 72 Hammersmith Road, London, United Kingdom W14 8TH, and registration of attendees and the distribution of voting slips will commence at the meeting venue at 9.45am.

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